World Journal of Anemia

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2017 | April-June | Volume 1 | Issue 2

EDITORIAL

Narendra Malhotra, Sourya Acharya

Anemia: Old Disease, New Solutions!

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:1] [Pages No:0 - 0]

PDF  |  DOI: 10.5005/wjoa-1-2-vi  |  Open Access |  How to cite  | 

RESEARCH ARTICLE

Shaheen Anjum, Nidhi Garg, Sri Beriwal, Anjum Parvez

High-dose Accelerated vs Low-dose Frequent Regime of Iron Sucrose Therapy in Antenatal and Postnatal Women with Iron Deficiency

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:5] [Pages No:31 - 35]

PDF  |  DOI: 10.5005/jp-journals-10065-0007  |  Open Access |  How to cite  | 

Abstract

Objective

To compare an accelerated high-dose (500 mg) vs low-dose (200 mg) regimen of intravenous iron sucrose in a cohort of iron-deficient anemic antenatal patients in terms of efficacy, safety, and compliance.

Materials and methods

In a prospective hospital-based study, antenatal and postnatal women with anemia attending Jawaharlal Nehru Medical College and Hospital, Aligarh, India, between December 2010 and December 2012 were enrolled. The inclusion criteria were all outpatient and admitted anemic antenatal women ≤ 36 weeks gestation and postnatal women with hemoglobin (Hb) below 10 gm/dL, or serum ferritin ≤ 30 μg/L or transferrin saturation ≤ 40% irrespective of prior oral iron therapy. Patients were excluded from the study if they were hemodynamically unstable, actively bleeding, having fever, or were nauseated or vomiting. Participants were assigned to control and study groups according to simple random sampling. Intravenous iron sucrose group I (500 mg)/group II (200 mg) was infused after test dose on alternate days for the calculated total dose in the study population. Blood and iron indices were measured at baseline and after 2 weeks of administration of last dose. The primary outcome of the study was to assess the rise in Hb and safety of high-dose intravenous iron sucrose.

Results

There was a statistically significant increase in Hb level in patients receiving either regimen, with larger mean increase in group I (2.7 ± 0.4) compared with group II (2.25 ± 6.39). Serum iron and serum ferritin also increased in both fortnightly (p < 0.001). Blood transfusion was avoided by 90.1% in severely anemic cases with Hb < 7. Hospital stay was reduced by 50% in group I.

Conclusion

The accelerated regimen of high-dose (500 mg) intravenous iron sucrose in anemic antenatal patients appears to be safe and effective in correcting anemia, restoring iron stores, and avoiding blood transfusion.

How to cite this article

Anjum S, Garg N, Beriwal S, Parvez A. High-dose Accelerated vs Low-dose Frequent Regime of Iron Sucrose Therapy in Antenatal and Postnatal Women with Iron Deficiency. World J Anemia 2017;1(2):31-35.

REVIEW ARTICLE

Sujal Munshi, Atul Munshi

Iron Deficiency Anemia in Pregnancy: Can We eradicate?

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:4] [Pages No:36 - 39]

PDF  |  DOI: 10.5005/jp-journals-10065-0008  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Munshi A, Munshi S. Iron Deficiency Anemia in Pregnancy: Can We eradicate? World J Anemia 2017;1(2):36-39.

REVIEW ARTICLE

Rajalakshmy Prasanth

Prevalence of Anemia in both Developing and Developed Countries around the World

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:4] [Pages No:40 - 43]

PDF  |  DOI: 10.5005/jp-journals-10065-0009  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Prasanth R. Prevalence of Anemia in both Developing and Developed Countries around the World. World J Anemia 2017;1(2):40-43.

REVIEW ARTICLE

Shreya Gupta, Neeti Swarup, Harita Sairam, Nidhi Sinha, Suresh S Nair

Orofacial Manifestations associated with Anemia

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:4] [Pages No:44 - 47]

PDF  |  DOI: 10.5005/jp-journals-10065-0010  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Gupta S, Gupta S, Swarup N, Sairam H, Sinha N, Nair SS. Orofacial Manifestations associated with Anemia. World J Anemia 2017;1(2):44-47.

REVIEW ARTICLE

Shreya Gupta, Nidhi Sinha, Neeti Swarup, Chandrani Sagolsem, Zoya Chowdhary

Atrophic Glossitis: Burning Agony of Nutritional Deficiency Anemia

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:3] [Pages No:48 - 50]

PDF  |  DOI: 10.5005/jp-journals-10065-0011  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Swarup N, Gupta S, Sagolsem C, Chowdhary Z, Gupta S, Sinha N. Atrophic Glossitis: Burning Agony of Nutritional Deficiency Anemia. World J Anemia 2017;1(2):48-50.

REVIEW ARTICLE

Prabhjot Kaur, Arun Bhatia, Kanav Midha, Mampi Debnath

Malaria: A Cause of Anemia and Its Effect on Pregnancy

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:12] [Pages No:51 - 62]

PDF  |  DOI: 10.5005/jp-journals-10065-0012  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Saxena R, Bhatia A, Midha K, Debnath M, Kaur P. Malaria: A Cause of Anemia and Its Effect on Pregnancy. World J Anemia. 2017;1(2):51-62.

CASE REPORT

Samarth Shukla, Sourya Acharya, Ajinkya Jamthe, Ankita Tamhane

Sickle Cell Anemia with Megaloblastic Crisis: Deficiency or Demand?

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:2] [Pages No:63 - 64]

PDF  |  DOI: 10.5005/jp-journals-10065-0013  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Acharya S, Shukla S, Jamthe A, Tamhane A. Sickle Cell Anemia with Megaloblastic Crisis: Deficiency or Demand? World J Anemia 2017;1(2):63-64.

CASE REPORT

Kanika Chopra

A Rare Case of Chronic Abruption-oligohydramnios Sequence at 16 Weeks Pregnancy with Compensated Severe Anemia

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:3] [Pages No:65 - 67]

PDF  |  DOI: 10.5005/jp-journals-10065-0014  |  Open Access |  How to cite  | 

Abstract

Aim

The aim of this article is to report a rare case of chronic abruption-oligohydramnios sequence (CAOS).

Background

Abruptio placentae is usually an acute event needing emergent measures for management, but may present with varied clinical features.

Case report

We describe a rare case of a 20-year-old primigravida at 16 weeks of gestation who presented with complaints of mild pain abdomen off and on for 1 month and minimal bleeding per vaginum for a day. Her vital signs were stable, but there was marked pallor. Obstetric examination revealed uterus corresponding to 20 to 22 weeks of gestation with raised basal tone. Ultrasound findings showed a dead fetus corresponding to 16 weeks of gestation with a large retroplacental collection of 12.5 × 7 cm. The patient was given three units of blood transfusion after which the patient went into spontaneous labor and delivered uneventfully 23 hours after admission.

Conclusion

Recognition of chronic abruption and prompt intervention in our case led to a favorable maternal outcome.

Clinical significance

The diagnosis of chronic abruption should be kept in mind in patients presenting with pain abdomen even in early pregnancy.

How to cite this article

Chopra K. A Rare Case of Chronic Abruption-oligohydramnios Sequence at 16 Weeks Pregnancy with Compensated Severe Anemia. World J Anemia 2017;1(2):65-67.

Quiz on Anemia in Pregnancy

Quiz on Anemia in Pregnancy

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:1] [Pages No:68 - 68]

PDF  |  DOI: 10.5005/wjoa-1-2-68  |  Open Access |  How to cite  | 

Quiz Questions on Anemia

Quiz Questions on Anemia

[Year:2017] [Month:April-June] [Volume:1] [Number:2] [Pages:2] [Pages No:69 - 70]

PDF  |  DOI: 10.5005/wjoa-1-2-69  |  Open Access |  How to cite  | 

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