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Volume  2 (2018)
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VOLUME 2 , ISSUE 3and4 ( July-December, 2018 ) > List of Articles

REVIEW ARTICLE

Twin-to-twin Transfusion Syndrome: An Overview

Richa Saxena, Kanav Midha

Keywords : Dizygotic, Fetus, Gestation, Monozygotic, Twin–twin transfusion syndrome

Citation Information : Saxena R, Midha K. Twin-to-twin Transfusion Syndrome: An Overview. World J Anemia 2018; 2 (3and4):96-102.

DOI: 10.5005/jp-journals-10065-0041

License: CC BY-NC 4.0

Published Online: 01-04-2020

Copyright Statement:  Copyright © 2018; The Author(s).


Abstract

Twin-to-twin transfusion syndrome (TTTS) is a severe problem that affects 10–15% of monochorionic (MC) multiple pregnancies. Connecting placental vessels on chorionic plate between donor and recipient twin is accountable for inequality of blood flow. There is an indication for the superiority of fetoscopic laser ablation over serial amnioreductions regarding survival and neurological outcome for stages II–IV TTTS. However, the optimal management of stage I is still debated. In this review, we discuss the basics of twin gestation, optimal management, pathophysiology, long-term neurodevelopmental outcome, and future aspects of TTTS.

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